Publications

This folder holds the following references to publications, sorted by year and author.

There are 56 references in this bibliography folder.

Head, E, Barrett, EG, Murphy, MP, Das, P, Nistor, M, Sarsoza, F, Glabe, CC, Kayed, R, Milton, S, Vasilevko, V, Milgram, NW, Agadjanyan, MG, Cribbs, DH, and Cotman, CW (2006).
Immunization with fibrillar Abeta(1-42) in young and aged canines: Antibody generation and characteristics, and effects on CSF and brain Abeta
Vaccine, 24(15):2824-34.

Milgram, NW, Siwak-Tapp, CT, Araujo, J, and Head, E (2006).
Neuroprotective effects of cognitive enrichment
Ageing Res Rev, 5(3):354-69.

Nippak, PM, Ikeda-Douglas, C, and Milgram, NW (2006).
Extensive spatial training does not negate age differences in response latency
Brain Res, 1070(1):171-88.

Studzinski, CM, Christie, L, Araujo, JA, Burnham, WM, Head, E, Cotman, CW, and Milgram, NW (2006).
Visuospatial function in the beagle dog: an early marker of cognitive decline in a model of human aging and dementia
Neurobiol Learn Mem, 86(2):197-204.

Araujo, JA, Studzinski, CM, and Milgram, NW (2005).
Further evidence for the cholinergic hypothesis of aging and dementia from the canine model of aging
Prog Neuropsychopharmacol Biol Psychiatry, 29(3):411-22.

Christie, L, Studzinski, CM, Araujo, JA, Leung, CS, Ikeda-Douglas, CJ, Head, E, Cotman, CW, and Milgram, NW (2005).
A comparison of egocentric and allocentric age-dependent spatial learning in the beagle dog
Prog Neuropsychopharmacol Biol Psychiatry, 29(3):361-9.

Milgram, NW, Head, E, Zicker, SC, Ikeda-Douglas, CJ, Murphey, H, Muggenburg, B, Siwak, C, Tapp, D, and Cotman, CW (2005).
Learning ability in aged beagle dogs is preserved by behavioral enrichment and dietary fortification: a two-year longitudinal study
Neurobiol Aging, 26(1):77-90.

Studzinski, CM, Araujo, JA, and Milgram, NW (2005).
The canine model of human cognitive aging and dementia: pharmacological validity of the model for assessment of human cognitive-enhancing drugs
Prog Neuropsychopharmacol Biol Psychiatry, 29(3):489-98.

Araujo, JA, Chan, AD, Winka, LL, Seymour, PA, and Milgram, NW (2004).
Dose-specific effects of scopolamine on canine cognition: impairment of visuospatial memory, but not visuospatial discrimination
Psychopharmacology (Berl), 175(1):92-8.

Ikeda-Douglas, CJ, Zicker, SC, Estrada, J, Jewell, DE, and Milgram, NW (2004).
Prior experience, antioxidants, and mitochondrial cofactors improve cognitive function in aged beagles
Vet Ther, 5(1):5-16.

Milgram, NW, Head, E, Zicker, SC, Ikeda-Douglas, C, Murphey, H, Muggenberg, BA, Siwak, CT, Tapp, PD, Lowry, SR, and Cotman, CW (2004).
Long-term treatment with antioxidants and a program of behavioral enrichment reduces age-dependent impairment in discrimination and reversal learning in beagle dogs
Exp Gerontol, 39(5):753-65.

Tapp, PD, Siwak, CT, Gao, FQ, Chiou, J, Black, SE, Head, E, Muggenburg, BA, Cotman, CW, Milgram, NW, and Su, M (2004).
Frontal lobe volume, function, and beta-amyloid pathology in a canine model of aging
J Neurosci, 24(38):8205-13.

Barsoum, SC, Milgram, W, Mackay, W, Coblentz, C, Delaney, KH, Kwiecien, JM, Kruth, SA, and Chang, PL (2003).
Delivery of recombinant gene product to canine brain with the use of microencapsulation
J Lab Clin Med, 142(6):399-413.

Milgram, NW (2003).
Cognitive experience and its effect on age-dependent cognitive decline in beagle dogs
Neurochem Res, 28(11):1677-82.

Nippak, PM, Chan, AD, Campbell, Z, Muggenburg, B, Head, E, Ikeda-Douglas, CJ, Murphey, H, Cotman, CW, and Milgram, NW (2003).
Response latency in Canis familiaris: mental ability or mental strategy?
Behav Neurosci, 117(5):1066-75.

Siwak, CT, Tapp, PD, Zicker, SC, Murphey, HL, Muggenburg, BA, Head, E, Cotman, CW, and Milgram, NW (2003).
Locomotor activity rhythms in dogs vary with age and cognitive status
Behav Neurosci, 117(4):813-24.

Tapp, PD, Siwak, CT, Estrada, J, Head, E, Muggenburg, BA, Cotman, CW, and Milgram, NW (2003).
Size and reversal learning in the beagle dog as a measure of executive function and inhibitory control in aging
Learn Mem, 10(1):64-73.

Tapp, PD, Siwak, CT, Estrada, J, Holowachuk, D, and Milgram, NW (2003).
Effects of age on measures of complex working memory span in the beagle dog (Canis familiaris) using two versions of a spatial list learning paradigm
Learn Mem, 10(2):148-60.

Chan, AD, Nippak, PM, Murphey, H, Ikeda-Douglas, CJ, Muggenburg, B, Head, E, Cotman, CW, and Milgram, NW (2002).
Visuospatial impairments in aged canines (Canis familiaris): the role of cognitive-behavioral flexibility
Behav Neurosci, 116(3):443-54.

Cotman, CW, Head, E, Muggenburg, BA, Zicker, S, and Milgram, NW (2002).
Brain aging in the canine: a diet enriched in antioxidants reduces cognitive dysfunction
Neurobiol Aging, 23(5):809-18.

Head, E and Torp, R (2002).
Insights into Abeta and presenilin from a canine model of human brain aging
Neurobiol Dis, 9(1):1-10.

Head, E, Liu, J, Hagen, TM, Muggenburg, BA, Milgram, NW, Ames, BN, and Cotman, CW (2002).
Oxidative damage increases with age in a canine model of human brain aging
J Neurochem, 82(2):375-81.

Milgram, NW, Head, E, Muggenburg, B, Holowachuk, D, Murphey, H, Estrada, J, Ikeda-Douglas, CJ, Zicker, SC, and Cotman, CW (2002).
Landmark discrimination learning in the dog: effects of age, an antioxidant fortified food, and cognitive strategy
Neurosci Biobehav Rev, 26(6):679-95.

Milgram, NW, Zicker, SC, Head, E, Muggenburg, BA, Murphey, H, Ikeda-Douglas, CJ, and Cotman, CW (2002).
Dietary enrichment counteracts age-associated cognitive dysfunction in canines
Neurobiol Aging, 23(5):737-45.

Siwak, CT, Murphey, HL, Muggenburg, BA, and Milgram, NW (2002).
Age-dependent decline in locomotor activity in dogs is environment specific
Physiol Behav, 75(1-2):65-70.